Final survival results from SPARTAN, a phase III study of apalutamide (APA) versus placebo (PBO) in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC).

Excelente resultado na no atraso da realização de quimioterapia , sobrevida global entorno de 73,9 meses x 59,9 meses do placebo , considerando subgrupo de pacientes que foram submetidos a terapia subsequente ou cross over , com analise de intenção de tratamento corrigida pelo IPCW ultrapassa a diferença de 21 meses 











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