(TAXOTERE E METFORMINA ) TAXOMET: A French prospective multicenter randomized controlled phase II study comparing docetaxel plus metformin versus docetaxel plus placebo in mCRPC.

APESAR DO BENEFÍCIO EM SOBREVIDA SER "END POINT" SECUNDÁRIO , APRESENTOU-SE NO BRAÇO DO TAXO-MET 24,6 MESES X 19,7 MESES TAXOTERE ISOLADO , IMPORTANTE QUE ERAM NÃO PACIENTES DIABETICOS , SEM HIPOGLICEMIA , E COM "END POINT" PRIMÁRIO DE REDUÇÃO DE PSA TOTAL EM 66% 














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